The USDA Animal and plant Health Inspection Service "Blue Book" consolidates the regulations and standards from the Animal Welfare Act and Animal Welfare Regulations.

The Animal Welfare Information Center (AWIC) is mandated by the Animal Welfare Act (AWA) to provide information for improved animal care and use in research, testing, teaching, and exhibition.

From the Johns Hopkins University Bloomberg School of Public Health, the Center for Alternatives to Animal Testing was created to promote and support alternative research techniques, emphasizing the 3Rs of replacement, reduction, and refinement.